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The review also discusses current trends in GLP-1 drug development, including recent clinical trials and industrial pipelines, with a focus on next-generation multi-target drugs

The disease is metastatic skin cancer, not lung cancer

Here we observed an increase of pRb phosphorylation in pancreatic islets treated with exendin-4 and a raise in E2f1 expression in Min6 cells treated with exendin-4, suggesting that -cell proliferation induced by Glp1r agonist could be under the control by the E2F1-pRb pathway